Hidden for centuries in a church in Tønsberg, Norway behind an Asgardian mural. Red Skull and HYDRA discover it. Scientist Armin Zola uses it to power weapons. Red Skull touches it directly—the Space Stone punishes him, teleporting him to Vormir. The Tesseract falls into the Arctic Ocean. Howard Stark recovers it; it enters S.H.I.E.L.D. custody.
At Project Pegasus, Mar-Vell harnesses it for a light-speed engine. Carol Danvers gains powers from the blast. Goose swallows the Tesseract. Later returns to S.H.I.E.L.D..
Loki steals it and opens a wormhole over New York for the Chitauri. Thor returns it to Asgard.
Loki grabs it from the vault during Asgard's destruction and escapes on the Statesman.
Thanos takes it from Loki on the Statesman, crushes the cube, and adds the Space Stone to the Gauntlet.